Analytical Tools and Databases for Metagenomics in the Next-Generation Sequencing Era
نویسندگان
چکیده
منابع مشابه
Analytical Tools and Databases for Metagenomics in the Next-Generation Sequencing Era
Metagenomics has become one of the indispensable tools in microbial ecology for the last few decades, and a new revolution in metagenomic studies is now about to begin, with the help of recent advances of sequencing techniques. The massive data production and substantial cost reduction in next-generation sequencing have led to the rapid growth of metagenomic research both quantitatively and qua...
متن کاملPathogen comparative genomics in the next-generation sequencing era: genome alignments, pangenomics and metagenomics.
As soon as whole-genome sequencing entered the scene in the mid-1990s and demonstrated its use in revealing the entire genetic potential of any given microbial organism, this technique immediately revolutionized the way pathogen (and many other fields of) research was carried out. The ability to perform whole-genome comparisons further transformed the field and allowed scientists to obtain info...
متن کاملMetagenomics: Tools and Insights for Analyzing Next-Generation Sequencing Data Derived from Biodiversity Studies
Advances in next-generation sequencing (NGS) have allowed significant breakthroughs in microbial ecology studies. This has led to the rapid expansion of research in the field and the establishment of "metagenomics", often defined as the analysis of DNA from microbial communities in environmental samples without prior need for culturing. Many metagenomics statistical/computational tools and data...
متن کاملNeSSM: A Next-Generation Sequencing Simulator for Metagenomics
BACKGROUND Metagenomics can reveal the vast majority of microbes that have been missed by traditional cultivation-based methods. Due to its extremely wide range of application areas, fast metagenome sequencing simulation systems with high fidelity are in great demand to facilitate the development and comparison of metagenomics analysis tools. RESULTS We present here a customizable metagenome ...
متن کاملBioinformatics in bacterial molecular epidemiology and public health: databases, tools and the next-generation sequencing revolution.
Advances in typing methodologies have been the driving force in the field of molecular epidemiology of pathogens. The development of molecular methodologies, and more recently of DNA sequencing methods to complement and improve phenotypic identification methods, was accompanied by the generation of large amounts of data and the need to develop ways of storing and analysing them. Simultaneously,...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Genomics & Informatics
سال: 2013
ISSN: 1598-866X,2234-0742
DOI: 10.5808/gi.2013.11.3.102